Indirect Immunofluorescence Test: EUROPLUS™ Primate Liver and Gliadin (GAF-3X) BIOCHIPs

Indirect Immunofluorescence Test: EUROPLUS™ Primate Liver and Gliadin (GAF-3X) BIOCHIPs from Euroimmun Medical Laboratory Diagnostics South Africa

By: Euroimmun Medical Laboratory Diagnostics South Africa  05-20-2011
Keywords: Diagnostics

  • - Detection of antibodies against endomysium and gliadin.
  • - Indications: gluten-sensitive enteropathy (celiac disease, non-tropical sprue), Duhring's herpetiform dermatitis.
  • - Initial dilution 1 : 10; conjugate class anti-human IgA or IgG, FITC-labelled.
  • - Autoantibodies against endomysium react with many types of tissue, e.g. primate oesophagus. The most suitable substrate, however, is primate liver: in the case of a positive sample, filamentous linings of the intralobular sinusoids react.
  • - With the gliadin (GAF-3X)-coated BIOCHIP, antibodies against gliadin can be analyzed in one and the same test procedure.
  • - Both anti-endomysium antibodies and antibodies against gliadin (class IgA) are reliable serological markers for an active gluten-sensitive enteropathy. Therefore, their determination can in many cases replace endoscopy and biopsy.
- ALSO AVAILABLE AS ELISA

Keywords: Diagnostics

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