Collagen is the most
abundant protein in our bodies, comprising around a third of our total
protein matter. In structure, it’s long and fibrous, which makes its
function quite different from that of globular proteins such as enzymes.
Bundles of collagen pack together to form long, thin fibrils and these
are a major component of the extra-cellular matrix that supports most
tissues and gives cells structure.
Native collagen is naturally insoluble in water. It can
be made soluble through a process involving partial hydrolysis and
extraction to yield hydrolysed collagen. Peptan is a type 1 hydrolysed
collagen. Type 1 indicates that it’s the same collagen as that found in
Scientific literature indicates that hydrolysed collagen
works on skin condition through a number of mechanisms. Postlethwaite
et al (1978) suggest that when type 1 collagens are digested, the
peptides which result are chemo-attractants for fibroblasts. Fibroblasts
produce collagen and are the main cells of the dermis (the central
layer of skin). It’s believed the collagen peptides then stimulate these
fibroblast cells to trigger the synthesis and reorganisation of new
Matsuda et al (2006) showed that hydrolysed collagen may
improve the mechanical strength of the skin by increasing the ratio of
decorins. These are proteins that interact with collagen and influence
collagen fibrillogenesis, therefore regulating excessive bundle-like
aggregation of collagen.
What were the main findings of the studies carried out on Peptan?
Peptan Hydrolysed Collagen is
clinically proven to enhance skin health. Positive findings from two
scientific studies give it all-important credibility for the nascent
nutri-cosmetic industry. Two new scientific studies in France and Japan,
looking at the effects of taking Peptan on skin condition, have shown
benefits across a range of indicators. Objective measurements showed
that women taking Peptan for between eight and 12 weeks had improved
skin moisture levels, suppleness and smoothness. It not only reduced the
number of micro relief furrows, but also prevented the formation of
Does the ingredient appeal to consumers?
Nègre: Collagen is one of the world’s
key ingredients for beauty-from-within products, and that’s why the
results of the Peptan Hydrolysed Collagen clinical studies are so
important. Valid scientific studies like these provide the proof
consumers have been waiting for and place Peptan at the forefront for
successful, new nutri-cosmetic product launches.
What beauty ingredient trends can you pinpoint for 2010/11?
The increasing awareness of
links between what we eat and our health and physical appearance means
that the concept of nutri-cosmetics or beauty foods offers attractive
opportunities to food, beverage and supplement producers.
With concrete scientific evidence that Peptan really
does improve the moisture content of the epidermis and helps to prevent
skin ageing, companies now have a springboard for successful, new
product launches targeting beauty from within.
Peptan is a natural, high-purity bioactive ingredient.
Its versatility and excellent organoleptic properties make it easy to
use and to incorporate in many kinds of foods and dietary supplements.
It’s highly soluble, clear and stable in solution.